DNA-PORPHYRIN INTERACTIONS PROBED BY INDUCED CD SPECTROSCOPY

Authors
KURODA R TANAKA H
Citation
R. Kuroda et H. Tanaka, DNA-PORPHYRIN INTERACTIONS PROBED BY INDUCED CD SPECTROSCOPY, Journal of the Chemical Society, Chemical Communications, (13), 1994, pp. 1575-1576
Citations number
12
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
13
Year of publication
1994
Pages
1575 - 1576
Database
ISI
SICI code
0022-4936(1994):13<1575:DIPBIC>2.0.ZU;2-6
Abstract
Detailed analysis by induced CD spectroscopy has revealed that the man ganese porphyrin, Mn(tmpyp), binds the major groove of AT or GC sequen ces in DNA, as well as the reported minor groove of AT sequences, with a preference that depends on the porphyrin to DNA base-pair molar rat io.