Arcanobacterium haemolyticum was recovered from 0.5% of throat culture
s of 3,922 patients seeking medical attention because of sore throat.
Most of the patients positive for A. haemolyticum were 15-25 years old
, and had fever (80%), lymphadenopathy (67%), pharyngeal exudate (69%)
or skin rash (23%). In this age group, 2% of the throat cultures prov
ed positive for A. haemolyticum. All A. haemolyticum strains were susc
eptible to penicillin, erythromycin, cephalexin and clindamycin, but r
esistant to trimethoprim/sulphamethoxazole. In half of the patients wi
th A. haemolyticum it was the only bacterial pathogen isolated, while
in the remainder, beta-haemolytic streptococci were also detected. As
expected, beta-haemolytic streptococci were much more frequent than A.
haemolyticum in the throat cultures.