ENANTIOMER SEPARATION USING MOBILE AND IMMOBILE CYCLODEXTRIN DERIVATIVES WITH ELECTROMIGRATION

Authors
MAYER S SCHURIG V
Citation
S. Mayer et V. Schurig, ENANTIOMER SEPARATION USING MOBILE AND IMMOBILE CYCLODEXTRIN DERIVATIVES WITH ELECTROMIGRATION, Electrophoresis, 15(6), 1994, pp. 835-841
Citations number
18
Categorie Soggetti
Biochemical Research Methods
Journal title
Electrophoresis → ACNP
ISSN journal
01730835
Volume
15
Issue
6
Year of publication
1994
Pages
835 - 841
Database
ISI
SICI code
0173-0835(1994)15:6<835:ESUMAI>2.0.ZU;2-E
Abstract
The principle of electrochromatography is applied to enantiomer separa tion with wall-coated capillaries of 50 mu m (ID). As chiral stationar y phase an immobilized polysiloxane containing chemically bonded monok is-6-O-octamethylene-permethyl-cyclodextrin (beta- or gamma-Chirasil-D ex) was used. The results are compared with the conventional method of adding cyclodextrin derivatives as chiral pseudostationary phase to t he running buffer.