ALPHA-DEUTERIUM ISOTOPE EFFECTS IN THE THERMOLYSIS OF BETA-HYDROXY ESTERS

Authors
QUIJANO J RESTREPO I GALLEGO LH YEPES MD
Citation
J. Quijano et al., ALPHA-DEUTERIUM ISOTOPE EFFECTS IN THE THERMOLYSIS OF BETA-HYDROXY ESTERS, Tetrahedron letters, 35(27), 1994, pp. 4735-4738
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
27
Year of publication
1994
Pages
4735 - 4738
Database
ISI
SICI code
0040-4039(1994)35:27<4735:AIEITT>2.0.ZU;2-W
Abstract
Alpha secondary isotope effects are determined experimentally by therm olysis of beta-hydroxyesters. These results are compatible with a chan ge of hybridization of carbon-2 from reactant to transition state (sp( 3) - sp(2)).