MODEL STUDIES TOWARDS THE INSECT ANTIFEEDANT JODRELLIN-A USING AN ORGANOSELENIUM MEDIATED CYCLIZATION REACTION

Authors
BLANEY WM CUNAT AC LEY SV MONTGOMERY FJ SIMMONDS MSJ
Citation
Wm. Blaney et al., MODEL STUDIES TOWARDS THE INSECT ANTIFEEDANT JODRELLIN-A USING AN ORGANOSELENIUM MEDIATED CYCLIZATION REACTION, Tetrahedron letters, 35(27), 1994, pp. 4861-4864
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
27
Year of publication
1994
Pages
4861 - 4864
Database
ISI
SICI code
0040-4039(1994)35:27<4861:MSTTIA>2.0.ZU;2-4
Abstract
An organoselenium mediated cyclization reaction of a beta-ketolactone (5), was used as the key step in an efficient synthesis of the molecul ar skeleton of the insect antifeedant Jodrellin A (1). The model compo und (2) shows significant activity against the African leaf worm Spodo ptera littoralis, at 1000 ppm.