On 21 July 7 1969, during the first manned lunar mission, Apollo 11, t
he first retroreflector array was placed on the moon, enabling highly
accurate measurements of the Earth-moon separation by means of laser r
anging. Lunar laser ranging (LLR) turns the Earth-moon system into a l
aboratory for a broad range of investigations, including astronomy, lu
nar science, gravitational physics, geodesy, and geodynamics. Contribu
tions from LLR include the three-orders-of-magnitude improvement in ac
curacy in the lunar ephemeris, a several-orders-of-magnitude improveme
nt in the measurement of the variations in the moon's rotation, and th
e verification of the principle of equivalence for massive bodies with
unprecedented accuracy. Lunar laser ranging analysis has provided mea
surements of the Earth's precession, the moon's tidal acceleration, an
d lunar rotational dissipation. These scientific results, current tech
nological developments, and prospects for the future are discussed her
e.