SIMULTANEOUS MEASUREMENT OF THE RENAL EXC RETION OF I-131 HIPPURAN AND (99M)TC-MAG3

This study describes methods of measuring simultaneously the renal exc retion of two radiopharmaceuticals and of evaluating their different k inetics. For quantification of the dynamic contributions of scattered radiation in a double-radionuclide study a high-resolution pure german ium detector was used. The geometry of the arrangement was a semi-shie lded whole-body counter according to E. Oberhausen. An intra-individua l comparison of the renal elimination of Tc-99m-MAG3 and I-131-Hippura n shows a systematic difference between both tracers depending on the time after injection, its average being around 11% between the 10th an d 20th min. The inter-individual comparison shows deviations from the mean between -29 and +20%.