NEW TECHNIQUE IN OPTICAL RESOLUTIONS

Authors
ACS M MRAVIK A FOGASSY E BOCSKEI Z
Citation
M. Acs et al., NEW TECHNIQUE IN OPTICAL RESOLUTIONS, Chirality, 6(4), 1994, pp. 314-320
Citations number
6
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chirality → ACNP
ISSN journal
08990042
Volume
6
Issue
4
Year of publication
1994
Pages
314 - 320
Database
ISI
SICI code
0899-0042(1994)6:4<314:NTIOR>2.0.ZU;2-Y
Abstract
The present paper illustrates the development of an advanced technique in optical resolution. Both of the amphetamine enantiomers can be obt ained by a two-step distillation in nearly quantitative yield without any loss of the resolving agent. It is proved that the second-order in teractions (H-bond) are sufficient for separation of enantiomers by di stillation. (C) 1994 Wiley-Liss, Inc.