SESQUITERPENE HYDROQUINONES FROM THE SPONGE RENIERA-MUCOSA

Authors
ZUBIA E ORTEGA MJ CARBALLO JL SALVA J
Citation
E. Zubia et al., SESQUITERPENE HYDROQUINONES FROM THE SPONGE RENIERA-MUCOSA, Tetrahedron, 50(27), 1994, pp. 8153-8160
Citations number
4
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
27
Year of publication
1994
Pages
8153 - 8160
Database
ISI
SICI code
0040-4020(1994)50:27<8153:SHFTSR>2.0.ZU;2-S
Abstract
The sponge Reniera mucosa contains eight new compounds, six of them of the panicein class (1-6) and two novel cyclohexenones renierin A (7) and renierin B (8), together with seven related known compounds (9-15) . Cyclohexenones 7 and 8 might be the biosynthetic intermediates from farnesyl precursors to paniceins. The structures were elucidated by in terpretation of spectral data and chemical interconversions. Four of t he new compounds (2, 3, 4 and 6) showed significant in vitro cytotoxic ity.