DNA CRUCIFORMS

Authors
KALLENBACH NR ZHONG M
Citation
Nr. Kallenbach et M. Zhong, DNA CRUCIFORMS, Current opinion in structural biology, 4(3), 1994, pp. 365-371
Citations number
77
Categorie Soggetti
Cytology & Histology",Biology
Journal title
Current opinion in structural biology → ACNP
ISSN journal
0959440X
Volume
4
Issue
3
Year of publication
1994
Pages
365 - 371
Database
ISI
SICI code
0959-440X(1994)4:3<365:DC>2.0.ZU;2-G
Abstract
Cruciforms represent a novel DNA state with unique physical and biolog ical properties, including the ability to undergo branch migration in appropriate sequence backgrounds. Recent results establish a preferred geometry of immobile cruciforms in Mg2+ solution, the rate of branch migration, and the binding properties of cruciforms for proteins and s mall molecule ligands. A structure has been determined for three-arm b ranches with unpaired bases at the branch.