QUALITY-CONTROL IN CLINICAL HEMORHEOLOGY - PRELIMINARY-STUDY BY 3 CENTERS

Clinical or pharmacological trials require reproducible laboratory tes ts. The aim of this work was to investigate the conditions of quality control of two laboratory tests, blood viscosity and red cell aggregat ion used for hemorheology trials in three centers. The results showed that viscosity measurements require 2 standards. For red cell aggregat ion, the control suspension standardized media (normal an pathological aggregation) showed a good intercentre reproducibility of the dissoci ation thresholds but a wide variability of aggregation times. Compleme ntary studies in 5 or 6 centres are planned in order to define nationa l standards of quality control