We report two patients presenting for thalamotomy in whom tremor was a
bolished for 8 h after propofol anaesthesia. Propofol has two contrast
ing actions. It may have an anti-Parkinsonion effect, abolishing abnor
mal limb movements. On other occasions, propofol is known to induce sp
ontaneous abnormal limb movements, as well as epileptiform activity. P
ropofol is probably best avoided for stereotactic procedures. It is di
fficult to reconcile these two opposing actions.