AN EFFICIENT BIOCATALYZED KINETIC RESOLUTION OF METHYL (Z)-3-ARYLSULPHINYLPROPENOATES

Authors
CARDELLICCHIO C NASO F SCILIMATI A
Citation
C. Cardellicchio et al., AN EFFICIENT BIOCATALYZED KINETIC RESOLUTION OF METHYL (Z)-3-ARYLSULPHINYLPROPENOATES, Tetrahedron letters, 35(26), 1994, pp. 4635-4638
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
26
Year of publication
1994
Pages
4635 - 4638
Database
ISI
SICI code
0040-4039(1994)35:26<4635:AEBKRO>2.0.ZU;2-P
Abstract
The enzymatic hydrolysis of racemic methyl (Z)- and (E)-3-arylsulphiny lpropenoates by several microbial lipases and alpha-chymotrypsin (alph a-CHT) was studied. High enantioselectivity values (up to 99%) were ob tained using (Z)-methyl esters.