PROTEIN-KINASE C-LIKE IMMUNOREACTIVITY IN GERBIL HIPPOCAMPUS AFTER A TRANSIENT CEREBRAL-ISCHEMIA

Authors
GAJKOWSKA B DOMANSKAJANIK K VIRON A
Citation
B. Gajkowska et al., PROTEIN-KINASE C-LIKE IMMUNOREACTIVITY IN GERBIL HIPPOCAMPUS AFTER A TRANSIENT CEREBRAL-ISCHEMIA, Folia histochemica et cytobiologica, 32(2), 1994, pp. 71-77
Citations number
19
Categorie Soggetti
Cytology & Histology
Journal title
Folia histochemica et cytobiologica → ACNP
ISSN journal
02398508
Volume
32
Issue
2
Year of publication
1994
Pages
71 - 77
Database
ISI
SICI code
0239-8508(1994)32:2<71:PCIIGH>2.0.ZU;2-P
Abstract
This study describes immunocytochemical distribution of the protein ki nase C (PKC) subspecies: alpha, beta and gamma in the CAI sector of ge rbil hippocampus. Immunolabelling was performed with 10 nm gold-antibo dy complexes against each of the PKC subspecies. The subspecies of PKC were expressed specifically in different populations of hippocampal c ells. An enhanced PKC immunoreactivity was noted in the animals after ischemia. We propose that this phenomenon reflects an activation of PK C in the early phase of brain ischemia.