I. Lorandmetze et al., HISTIOCYTIC NECROTIZING LYMPHADENITIS IN BRAZIL - REPORT OF A CASE AND REVIEW OF THE LITERATURE, Pathology international, 44(7), 1994, pp. 548-550
Histiocytic necrotizing lymphadenitis is rare outside Japan, including
Brazil, despite the many Japanese immigrants and descendants who live
there. The authors describe the case of a 32 year old white female, w
ho presented with cervical lymph node enlargement and severe anemia. H
istological findings of the lymph node were typical for Kikuchi's dise
ase. Bone marrow showed hyperplasia of normoblasts, suggesting hemolys
is, but a Coombs' test was negative. The patient had a spontaneous res
olution of all symptoms and has remained asymptomatic for 3 years. Esp
ecially where this disease is rarely reported, it is important to reco
gnize it, in order to avoid a misdiagnosis of malignant lymphoma.