SHORT-TERM BIOEFFECTS OF EXTRACORPOREAL SHOCKWAVE LITHOTRIPSY

Safety guidelines for shockwave delivery during extracorporeal shockwa ve lithotripsy (SWL) are not yet clear. Renal functions were assessed by using urinary N-acetyl-beta-D-glucosaminidase (NAG), lactate dehydr ogenase (LDH), alanine aminotransferase (ALT; EC.2.6.1.2), aspartate a minotransferase (AST; EC. 2.6.1.1), and gamma-glutamyltransferase (GGT ) as well as sodium, potassium, and calcium concentrations in respect to tubular functions after SWL with the Dornier MFL 5000 unit in 32 pa tients. In order to monitor glomerular function, we determined microal buminuria. Transient glomerular and tubular damage occurs in SWL-treat ed kidneys. The minimum interval between two shockwave treatments shou ld be at least 7 days.