A ROLE FOR SECRETORY PHOSPHOLIPASE A(2) AND C-REACTIVE PROTEIN IN THEREMOVAL OF INJURED CELLS

Authors
HACK CE WOLBINK GJ SCHALKWIJK C SPEIJER H HERMENS WT VANDENBOSCH H
Citation
Ce. Hack et al., A ROLE FOR SECRETORY PHOSPHOLIPASE A(2) AND C-REACTIVE PROTEIN IN THEREMOVAL OF INJURED CELLS, Immunology today, 18(3), 1997, pp. 111-115
Citations number
48
Categorie Soggetti
Immunology
Journal title
Immunology today → ACNP
ISSN journal
01675699
Volume
18
Issue
3
Year of publication
1997
Pages
111 - 115
Database
ISI
SICI code
0167-5699(1997)18:3<111:ARFSPA>2.0.ZU;2-Q
Abstract
The acute phase response is initiated in response to infection or phys ical trauma and is characterized by an increase in the levels of some plasma proteins. Here, Erik Hack and colleagues suggest that the combi ned actions of two of these acute phase proteins, secretory phospholip ase A(2) and C-reactive protein, may serve to promote phagocytosis of injured cells and tissue debris, thereby enhancing inflammation and ti ssue damage.