NEW BIOMATERIALS THROUGH SURFACE SEGREGATION PHENOMENON - NEW QUATERNARY AMMONIUM-COMPOUNDS AS ANTIBACTERIAL AGENTS

Authors
NOHR RS MACDONALD JG
Citation
Rs. Nohr et Jg. Macdonald, NEW BIOMATERIALS THROUGH SURFACE SEGREGATION PHENOMENON - NEW QUATERNARY AMMONIUM-COMPOUNDS AS ANTIBACTERIAL AGENTS, Journal of biomaterials science. Polymer ed., 5(6), 1994, pp. 607-619
Citations number
25
Categorie Soggetti
Engineering, Biomedical","Polymer Sciences","Materials Science, Biomaterials
Journal title
Journal of biomaterials science. Polymer ed. → ACNP
ISSN journal
09205063
Volume
5
Issue
6
Year of publication
1994
Pages
607 - 619
Database
ISI
SICI code
0920-5063(1994)5:6<607:NBTSSP>2.0.ZU;2-Q
Abstract
Five new trisiloxane quaternary ammonium compounds were synthesized fr om hydrotrisiloxane with allyl glycidyl ether to yield the epoxy funct ion. Various amines were then reacted to yield trisiloxane amines whic h were further reacted to methyl substitute or oxidize the beta-carbon s in order to provide thermal stability. These new compounds were empl oyed as melt additives in a nonwoven polypropylene fiber extrusion pro cess to produce, through surface segregation, a new biomaterial with a ntibacterial properties.