Jm. Risco et al., A CASE OF CORNEAL KELOID - CLINICAL, SURGICAL, PATHOLOGICAL, AND ULTRASTRUCTURAL CHARACTERISTICS, British journal of ophthalmology, 78(7), 1994, pp. 568-571
A 69-year-old patient developed a localised, whitish, elevated, cornea
l lesion with a smooth and glistening surface following trauma, withou
t evidence of corneal perforation. Twelve months later, the lesion sho
wed evidence of slow growth. An excisional biopsy was then performed.
Histopathologically, the lesion was covered by non-keratinised squamou
s epithelium and was comprised of randomly oriented collagen fibres co
ntaining active fibroblasts. Blood vessels were noted deep in the lesi
on. Ultrastructurally, the cell population was formed by fibroblasts a
nd myofibroblasts, similar to keloids of the skin. The clinical, patho
logical, and ultrastructural features of the corneal lesion are compat
ible with a corneal keloid.