Av. Mazurin et al., CHARACTERISTICS OF LIPID AND PHOSPHOLIPID -COMPOSITION OF THE SERUM AND RED-CELL MEMBRANES IN CHILDREN WITH HEMORRHAGIC VASCULITIS, Gematologia i transfuziologia, 39(2), 1994, pp. 37-39
Thin-layer chromatography examination of serum and red cell membrane l
ipids and phospholipids has been conducted in 37 children with hemorrh
agic vasculitis. The authors found: huperlipidemia resultant from high
concentrations of triglycerides, changes in phospholipid fractions du
e to a relative rise in the level of phosphatidylethanolamine, altered
spectrum of red cell membrane lipids due to a significant increase in
free cholesterol against low triglycerides. The above shifts may caus
e hypercoagulation and microcirculatory affections. The conclusion is
made on the necessity of correcting impaired lipid spectrum of blood p
lasma and red cell membrane when conducting basic therapy of hemorrhag
ic vasculitis.