Qh. Siraj et Ajw. Hilson, DIAGNOSTIC-VALUE OF RADIONUCLIDE PHALLOGRAPHY WITH INTRAVENOUS VASODILATOR STRESS IN THE EVALUATION OF ARTERIOGENIC IMPOTENCE, European journal of nuclear medicine, 21(7), 1994, pp. 651-657
Arteriogenic impotence is a major cause of organic erectile dysfunctio
n. We evaluated the diagnostic value of quantitative radionuclide phal
lography with intravenous pharmacological stress in screening impotent
patients for penile arterial inadequacy. Using technetium-99m labelle
d autologous erythrocytes, dynamic scintigraphy of the penile blood po
ol was performed. Penile haemodynamic changes following intravenous in
jection of the vasodilator isoxsuprine hydrochloride were assessed by
quantitation of penile blood flow and volume. Forty-seven impotent pat
ients (11 psychogenic, 24 arteriogenic, 10 venogenic, 2 endocrine) wer
e studied. Arteriogenic impotent patients demonstrated a lesser degree
of increase in penile blood flow and volume than impotent patients wi
th uncompromised penile arterial inflow. Quantitation of penile blood
flow and volume yielded a high diagnostic accuracy (>90%). Radionuclid
e phallography with intravenous vasodilator stress forms a simple and
accurate method for evaluating the functional integrity of penile arte
rial inflow.