INTERFERON-ALPHA(2B) TREATMENT IN HEPATITIS-B CARRIERS - EFFECT ON HEPATITIS-B VIRUS-DNA LEVELS IN CHILDREN INFECTED WITH DIFFERENT GENOTYPES

Authors
SANGFELT P NORDER H MAGNIUS LO ALAEUS A CARLSSON T REICHARD O
Citation
P. Sangfelt et al., INTERFERON-ALPHA(2B) TREATMENT IN HEPATITIS-B CARRIERS - EFFECT ON HEPATITIS-B VIRUS-DNA LEVELS IN CHILDREN INFECTED WITH DIFFERENT GENOTYPES, Acta paediatrica, 86(2), 1997, pp. 135-137
Citations number
14
Categorie Soggetti
Pediatrics
Journal title
Acta paediatrica → ACNP
ISSN journal
08035253
Volume
86
Issue
2
Year of publication
1997
Pages
135 - 137
Database
ISI
SICI code
0803-5253(1997)86:2<135:ITIHC->2.0.ZU;2-5
Abstract
Eleven hepatitis B virus (HBV) carrier children, infected with genotyp es A-D, were treated with interferon-alpha. Two children had a sustain ed loss of hepatitis B e-antigen and HBV DNA. They were infected with the non-Asian genotypes A and D, and had low HBV DNA and high ALT leve ls in serum before treatment. However, HBV DNA titres decreased during treatment also in children infected with the East-Asian genotypes B a nd C.