EFFECT OF CALCIUM-ION CONTENT ON THE INTERACTION OF ALPHA-LACTALBUMINWITH FLUORIDE IONS

Authors
WIECZOREK P SAMUJLO D MACHOY Z
Citation
P. Wieczorek et al., EFFECT OF CALCIUM-ION CONTENT ON THE INTERACTION OF ALPHA-LACTALBUMINWITH FLUORIDE IONS, Fluoride, 27(3), 1994, pp. 145-150
Citations number
11
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Fluoride → ACNP
ISSN journal
00154725
Volume
27
Issue
3
Year of publication
1994
Pages
145 - 150
Database
ISI
SICI code
0015-4725(1994)27:3<145:EOCCOT>2.0.ZU;2-O
Abstract
The effect of calcium ions in alpha-lactalbumin on the binding of fluo ride ions was investigated. It has been disclosed that at pH 4.6 both alpha-lactalbumin and apo-alpha-lactalbumin, when deprived of calcium ions, fail to bind fluoride ions. At pH 3.7 the alpha-lactalbumin mole cule and its calcium-free form of apo-alpha-lactalbumin do bind fluori de ions but the mechanism of this bindings is variable.