CONFIRMATION OF NEPHROTROPISM AND NEPHROPATHOGENICITY OF 3 LOW-PATHOGENIC CHICKEN-ORIGIN INFLUENZA-VIRUSES FOR CHICKENS

Citation
De. Swayne et Dj. Alexander, CONFIRMATION OF NEPHROTROPISM AND NEPHROPATHOGENICITY OF 3 LOW-PATHOGENIC CHICKEN-ORIGIN INFLUENZA-VIRUSES FOR CHICKENS, Avian pathology, 23(2), 1994, pp. 345-352
Citations number
29
Categorie Soggetti
Veterinary Sciences
Journal title
ISSN journal
03079457
Volume
23
Issue
2
Year of publication
1994
Pages
345 - 352
Database
ISI
SICI code
0307-9457(1994)23:2<345:CONANO>2.0.ZU;2-3
Abstract
Specific pathogen-free chickens were inoculated intravenously with one of three low-pathogenic chicken-origin influenza virus isolates. On d ay 5 post-inoculation, most chickens had gross and histological kidney lesions. Influenza virus of high titre was recovered from the kidneys and influenza nucleoprotein, detected immunohistochemically was local ized in necrotic renal tubule epithelium. These data indicate low-path ogenic influenza viruses can be nephrotropic and nephropathogenic, and corroborate gross observations from some low-pathogenic influenza out breaks in laying hens.