AN ANALYSIS OF IRON-DEXTRAN COMPLEXES BY MOSSBAUER-SPECTROSCOPY AND POSITRON-ANNIHILATION TECHNIQUE

The combination of two modern spectroscopic techniques was used for co mparative microstructural analysis of several iron-dextran complexes w hich were used or elaborated as drugs for treatment of iron-deficiency anemias. Slight variations of the iron electronic and magnetic struct ure in different iron-dextran complexes were detected by Mossbauer spe ctroscopy. The differences of iron core structure and size were shown in studied complexes also. Variations of dextran structure were detect ed by the positron annihilation technique for investigated iron-dextra n complexes. These results were considered with histological and histo chemical data for iron-dextran complexes to compare the differences of their microstructural variations and biochemical pathways.