QUANTITATION OF PORTOSYSTEMIC SHUNTING IN DOGS BY ULTRASOUND-GUIDED INJECTION OF TC-99M-MACROAGGREGATES INTO A SPLENIC VEIN

Citation
Hp. Meyer et al., QUANTITATION OF PORTOSYSTEMIC SHUNTING IN DOGS BY ULTRASOUND-GUIDED INJECTION OF TC-99M-MACROAGGREGATES INTO A SPLENIC VEIN, Research in Veterinary Science, 57(1), 1994, pp. 58-62
Citations number
26
Categorie Soggetti
Veterinary Sciences
ISSN journal
00345288
Volume
57
Issue
1
Year of publication
1994
Pages
58 - 62
Database
ISI
SICI code
0034-5288(1994)57:1<58:QOPSID>2.0.ZU;2-I
Abstract
A technique is described for the ultrasound-guided injection of Tc-99m -macroaggregates into a splenic vein in order to quantitate portosyste mic collateral circulation. The fraction of portal blood by-passing th e liver was derived from the radioactivity trapped in the liver and lu ngs and was expressed as the shunt index (SI). The method was tested i n healthy dogs without shunting, and in dogs with single hereditary po rtosystemic shunts before and one month after surgical closure of the shunt. The mean SI was 0.01 (range 0.01 to 0.05) in healthy dogs and 0 .94 (0.69 to 1.00) in dogs with hereditary shunts. After partial closu re of the shunts the SI decreased to 0.25 (0.03 to 0.70). There was a significant positive correlation between the logarithms of the concent ration of ammonia in plasma and the SI (r=0.87, P<0.001).