A total of 54 patients with culturally proven tropical dermatomycoses,
comprising 23 with various types of dermatophytoses, one with foot in
fection due to Trichosporon beigelii and one with foot infection due t
o Geotrichum candidum, two with candidoses of the groin and 27 with pi
tyriasis versicolor, were included in a clinical trial of efficacy of
1% isoconazole cream (Travogen(R), Schering, Berlin, Germany). Five pa
tients were not evaluable. A clinical and mycological cure was achieve
d in 29 cases in 3-4 weeks. In 15 (31%) of the remaining patients trea
tment was required for 5-6 weeks, while another three patients require
d treatment for 8 weeks. In two patients the disease proved to be resi
stant to treatment with the drug.