Mj. Campbell et al., INVESTIGATION OF THE STABILITY AND SELECTIVITY OF PHENYLALANINE TRANSPORT ACROSS A SUPPORTED LIQUID MEMBRANE, Journal of chemical technology and biotechnology, 60(3), 1994, pp. 263-273
A supported liquid membrane system was investigated for the carrier me
diated transport of phenylalanine to more fully understand the contrad
ictory effects, described in the literature, of chloride ion concentra
tion in the aqueous phases on the stability of the system. The role of
the organic phase and its interaction with carrier and support materi
al was considered. The carrier mediated transport was comparable to an
enzyme mediated process. Kinetic studies were undertaken and the data
interpreted in a manner appropriate to biological transport processes
to consider the transport process at a molecular level. The system wa
s shown to deviate from a direct 1:1 exchange process between phenylal
anine and chloride and had a high degree of selectivity with respect t
o phenylalanine.