MULTIPLE NEVOID SPIRADENOMAS

This report delineates a new clinical presentation of multiple benign spiradenoma (BS), a diffuse linear nevoid pattern. A 16-year-old girl, in otherwise good health, had many papulonodular lesions, varying in color from blue-gray to bright red, disposed linearly on the right hal f of her body, involving the periorbital region, cheek, lateral side o f the neck, trunk, linea alba, right thigh, and leg. Only a few nodule s were slightly painful. Lesions were reported to be present at birth; no family members had similar lesions, either in solitary or multiple form. Excisional biopsies of three lesions from the neck, abdomen, an d leg, respectively, were performed; histologically, all three samples showed a picture of BS. In some areas, the tumor was directly connect ed to a pilosebaceous unit. Furthermore, a focal area with pilar diffe rentiation at the periphery of the lobules was observed, which might s uggest that BS can differentiate toward various cutaneous adnexal stru ctures. Our patient probably is the first one reported with diffuse li near nevoid lesions of BS, present at birth and involving the right ha lf of the body.