EFFECTS OF ALUMINUM(III) AND FLUORIDE ON THE DEMINERALIZATION OF BOVINE ENAMEL - A LONGITUDINAL MICRORADIOGRAPHIC STUDY

Longitudinal microradiography has been used to determine inhibiting ef fects of aluminum (III), Al, and fluoride on mineral loss from slices of bovine enamel exposed to a demineralizing solution 4 h daily for 35 days. Inhibitor treatment was 5 min four times daily. For the remaini ng time, the samples were immersed in a neutral calcium phosphate solu tion which allowed neither remineralization nor demineralization. This study indicates that a l-mM (27 ppm) solution of Al in a 0.1-M lactat e solution: pH 5, has an inhibitory effect on the in vitro demineraliz ation of bovine enamel. Application of this solution alternating with 20 mM (380 ppm) fluoride gave the same total inhibition as treatment w ith 20 mM fluoride alone.