M. Coibion et al., IS THERE A ROLE FOR CERVICOGRAPHY IN THE DETECTION OF PREMALIGNANT LESIONS OF THE CERVIX UTERI, British Journal of Cancer, 70(1), 1994, pp. 125-128
The characteristics of cervicography and the Papanicolaou smear test h
ave been compared for the detection of cervix lesions classified as CI
N I or more. A total of 4,015 women were entered into the study. The s
ensitivity of cervicography is significantly higher (McNemar test, P<0
.0001), but its specificity remains significantly lower (McNemar test,
P<0.0001), and its higher sensitivity does not apply to lesions class
ified as CIN II or more (high-grade lesions). Hence, if patients with
a positive screen result are to be referred for colposcopy-biopsy, cer
vicography is not a suitable alternative to the smear test for the scr
eening of cervical cancer. However, cervicography can be envisaged as
a complementary tool to the smear test because of(a) its higher capabi
lity to detect high-grade lesions among women less than 35 years old a
nd (b) its potential superiority in following low-grade lesions. It ma
y also serve as a tool for quality assurance audit of the smear test.