MEMORY CONSOLIDATION AND THE MEDIAL TEMPORAL-LOBE - A SIMPLE NETWORK MODEL

Some forms of memory have been shown to depend on a system of medial t emporal lobe structures that includes the hippocampus and the adjacent cortical areas (entorhinal, perirhinal, and parahippocampal cortex). The role of this system is only temporary, however, as indicated by th e fact that, after damage to the medial temporal lobe, recent memories are impaired but very remote memories are intact. Here we review the evidence that the medial temporal lobe memory system is involved in a process of consolidation: memories are initially dependent on this sys tem but gradually become established in other areas of the brain. We t hen review some of the ideas that have been proposed about the phenome non of consolidation and suggest a synthesis of these views. Finally, we describe a simple neural network model that captures some key featu res of consolidation.