ATYPICAL VARICELLA-ZOSTER INFECTION IN PERSONS WITH HIV-INFECTION

Four patients with HIV infection and severe immunodeficiency are descr ibed who developed atypical varicella zoster lesions. Three of the pat ients presented with chronic varicella zoster lesions. In two of them such lesions were hyperkeratotic. All three patients had been treated initially with subtherapeutic doses of acyclovir. In one of the patien ts the lesions were clinically resistant to high dose acyclovir treatm ent and disappeared only when renal insufficiency developed during fos carnet-famcyclovir treatment. One patient developed a disseminated var icella zoster infection.