BIOLOGICAL CHEMISTRY OF ALUMINUM STUDIED USING AL-26 AND ACCELERATOR MASS-SPECTROMETRY

Authors
DAY JP BARKER J KING SJ MILLER RV TEMPLAR J LILLEY JS DRUMM PV NEWTON GWA FIFIELD LK STONE JOH ALLAN GL EDWARDSON JA MOORE PB FERRIER IN PRIEST ND NEWTON D TALBOT RJ BROCK JH SANCHEZ L DOBSON CB ITZHAKI RF RADUNOVIC A BRADBURY MWB
Citation
Jp. Day et al., BIOLOGICAL CHEMISTRY OF ALUMINUM STUDIED USING AL-26 AND ACCELERATOR MASS-SPECTROMETRY, Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms, 92(1-4), 1994, pp. 463-468
Citations number
32
Categorie Soggetti
Physics, Nuclear","Nuclear Sciences & Tecnology","Instument & Instrumentation
Journal title
Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms → ACNP
ISSN journal
0168583X
Volume
92
Issue
1-4
Year of publication
1994
Pages
463 - 468
Database
ISI
SICI code
0168-583X(1994)92:1-4<463:BCOASU>2.0.ZU;2-D
Abstract
Developments in sample preparation and presentation for accelerator ma ss spectrometry now permit the determination of Al-26/Al-27 ratios in biological materials with an accuracy of ca. 2%. We describe the use o f Al-26 as a tracer for aluminium, in a number of biological experimen ts which demonstrate the power of this technique to determine Al conte nt and distribution within complex chemical and biological systems, an d to investigate the kinetics and mechanisms of Al-transport pathways. Applications to human, animal and cellular systems are described.