OPPORTUNISTIC INFECTION DURING TREATMENT WITH LOW-DOSE METHOTREXATE

Authors
LEMENSE GP SAHN SA
Citation
Gp. Lemense et Sa. Sahn, OPPORTUNISTIC INFECTION DURING TREATMENT WITH LOW-DOSE METHOTREXATE, American journal of respiratory and critical care medicine, 150(1), 1994, pp. 258-260
Citations number
22
Categorie Soggetti
Emergency Medicine & Critical Care","Respiratory System
Journal title
American journal of respiratory and critical care medicine → ACNP
ISSN journal
1073449X
Volume
150
Issue
1
Year of publication
1994
Pages
258 - 260
Database
ISI
SICI code
1073-449X(1994)150:1<258:OIDTWL>2.0.ZU;2-2
Abstract
Two patients receiving low dose methotrexate, one with rheumatoid arth ritis and the other with pityriasis rubra pilaris, developed dissemina ted histoplasmosis and Mycobacterium avium intracellulare pneumonia, r espectively. Twenty-three cases of opportunistic infection in patients receiving low dose methotrexate have been reported previously, with P neumocystis carinii pneumonia being the most common infection (10 of 2 3, 43%). Patients receiving low dose methotrexate are at risk for oppo rtunistic infection despite normal leukocyte counts.