NORMAL SERUM RELAXIN IN WOMEN WITH DISABLING PELVIC PAIN DURING PREGNANCY

As part of a case control within cohort study 472 pregnant women answe red a questionnaire post partum. Serum relaxin concentrations were mea sured by a homologous ELISA in samples collected from the women in the 30th week of pregnancy. Serum relaxin concentrations were not associa ted with pregnancy-associated pelvic pain. Thus, normal pregnant women without pelvic pain (n = 118) had mean concentrations of 343 pg/ml co mpared to 332 pg/ml in women (n = 59) with pelvic pain and some restri ction in daily activities and to 349 pg/ml in women (n = 9) with sever e pregnancy-induced pelvic pain. The present results do not suggest a role for relaxin in symptom-giving pelvic relaxation during human preg nancy.