EVALUATION OF WHETHER USING HCG TO STIMULATE OOCYTE RELEASE HELPS OR DECREASES PREGNANCY RATES FOLLOWING INTRAUTERINE INSEMINATION

The study's objective was to determine if using human chorionic gonado tropin (hCG) as a timing method for intrauterine insemination (IUI) in patients who make mature follicles but have cervical factor problems has a negative effect on pregnancy rates (PRs) (possibly by releasing an immature oocyte), or increases the rate of luteinized unruptured fo llicles (LUF). Patients were offered hCG or natural release after an e xplanation of the theoretical advantages and disadvantages. Intrauteri ne insemination was performed 36-40 h after hCG; timing of IUI with hC G was based on day of luteinizing hormone (LH) surge modified by serum progesterone (P). Incidence of LUF in those taking hCG - 5/116 (4.3%) ; 0/33 without hCG. Pregnancies - 24/116 (20%) with hCG; 3/30 (10%) wi thout hCG. No statistical differences in these rates were found. Thus, using hCG for more convenient timing for IUI in nonsuperovulated cycl es does not decrease the PR or cause a high incidence of LUF.