PLASMA BETA-ENDORPHIN CONCENTRATIONS AND ANALGESIA MUSCLE-RELAXATION IN THE NEWBORN-INFANT SUPPORTED BY MECHANICAL VENTILATION

Authors
IONIDES SP WEISS MG ANGELOPOULOS M MYERS TF HANDA RJ
Citation
Sp. Ionides et al., PLASMA BETA-ENDORPHIN CONCENTRATIONS AND ANALGESIA MUSCLE-RELAXATION IN THE NEWBORN-INFANT SUPPORTED BY MECHANICAL VENTILATION, The Journal of pediatrics, 125(1), 1994, pp. 113-116
Citations number
15
Categorie Soggetti
Pediatrics
Journal title
The Journal of pediatrics → ACNP
ISSN journal
00223476
Volume
125
Issue
1
Year of publication
1994
Pages
113 - 116
Database
ISI
SICI code
0022-3476(1994)125:1<113:PBCAAM>2.0.ZU;2-2
Abstract
We evaluated the effects of pancuronium and opiates on plasma a-endorp hin concentrations in 25 infants supported by mechanical ventilation. Infants receiving opiate were randomly assigned to receive either fent anyl or morphine. There was no change in beta-endorphin concentrations after administration of pancuronium, whereas both fentanyl and morphi ne reduced a-endorphin concentrations by approximately 60%.