NEPHROCALCINOSIS AND NEPHROLITHIASIS IN INFANTS WITH CONGESTIVE-HEART-FAILURE TREATED WITH FUROSEMIDE

Citation
Us. Alon et al., NEPHROCALCINOSIS AND NEPHROLITHIASIS IN INFANTS WITH CONGESTIVE-HEART-FAILURE TREATED WITH FUROSEMIDE, The Journal of pediatrics, 125(1), 1994, pp. 149-151
Citations number
15
Categorie Soggetti
Pediatrics
Journal title
ISSN journal
00223476
Volume
125
Issue
1
Year of publication
1994
Pages
149 - 151
Database
ISI
SICI code
0022-3476(1994)125:1<149:NANIIW>2.0.ZU;2-U
Abstract
Nephrocalcinosis and nephrolithiasis developed in five children after furosemide therapy for congestive heart failure. In four children rena l calcifications were detected by ultrasonography and in one by autops y. Discontinuation of the loop diuretic in three children resulted in resolution of the calcifications in two of the patients. Residual rena l morbidity included reduced creatinine clearance, microscopic hematur ia, and hypercalciuria. The phenomenon of renal calcifications associa ted with furosemide treatment is more frequent than previously recogni zed.