Sa. Koff et al., THE ASSESSMENT OF OBSTRUCTION IN THE NEWBORN WITH UNILATERAL HYDRONEPHROSIS BY MEASURING THE SIZE OF THE OPPOSITE KIDNEY, The Journal of urology, 152(2), 1994, pp. 596-599
We measured the size of the normal kidney opposite a unilateral hydron
ephrotic kidney in infants to determine if compensatory changes occurr
ed and could be used as a diagnostic test for defining or excluding ob
struction. Comparison of subgroups of neonates with unilateral hydrone
phrosis or multicystic renal dysplasia to normal controls demonstrated
that compensatory changes do occur in the normal kidney. Normal kidne
ys opposite obstructed hydronephrotic kidneys requiring surgery became
larger than normal for age. Normal kidneys opposite nonobstructed poo
rly functioning hydronephrotic kidneys whose function rapidly improved
were smaller than normal for age. These changes in renal growth by th
e normal newborn kidney reflect renal counterbalance, which is exagger
ated in this age group and which may be used to corroborate rapid chan
ges in renal function caused by the presence or absence of obstruction
. By plotting serial measurements of normal renal length on a renal gr
owth chart, the diagnosis of obstruction in newborn hydronephrosis can
be facilitated and the clinical management of the patient improved.