ACINIC CELL-CARCINOMA OF SALIVARY-GLANDS

Objective: To test the prognostic ability of flow cytometry and counts of silver-enhanced intranuclear nucleolar organizing regions (AgNORs) in acinic cell carcinoma. Design: Using statistical methods to establ ish if analysis of DNA content, percentage DNA synthetic (S)-phase, an d the AgNOR counts on 45 cases of acinic cell carcinoma with clinical follow-up ranging from 10 to 379 months are predictors of time to recu rrence or time to death due to acinic cell carcinomas. Main Outcome Me asures: Whether tumors with low AgNOR counts and diploid DNA are favor able acinic cell carcinomas and the converse, aneuploid DNA and elevat ed AgNOR count, predict unfavorable neoplasms.