MAMCAT - AN EXPERT-SYSTEM FOR DISTINGUISHING BETWEEN MAMMILLARY AND CATENARY COMPARTMENTAL-MODELS

Citation
Anbk. Dechizelle et Jj. Distefano, MAMCAT - AN EXPERT-SYSTEM FOR DISTINGUISHING BETWEEN MAMMILLARY AND CATENARY COMPARTMENTAL-MODELS, Computers in biology and medicine, 24(3), 1994, pp. 189-204
Citations number
18
Categorie Soggetti
Mathematical Methods, Biology & Medicine","Engineering, Biomedical","Computer Science Interdisciplinary Applications
ISSN journal
00104825
Volume
24
Issue
3
Year of publication
1994
Pages
189 - 204
Database
ISI
SICI code
0010-4825(1994)24:3<189:M-AEFD>2.0.ZU;2-Y
Abstract
MAMCAT is a user-friendly, interactive, graphics-based PC program for addressing a common compartmental model discrimination problem in the framework of model indistinguishability theory: can mammillary and cat enary models of the same order be distinguished from each other? The s oftware is designed to teach the theory and solve specific problems. T he user is guided step-by-step through definitions, examples, theory a nd problem solution. Topological properties are used first to screen o ut some distinguishable models and thereby reduce the number of candid ates for indistinguishability. Transfer function analysis is then used to explore the remaining candidates. Analytical results for up to 5-c ompartment models are given and a more general algorithm is induced fr om these results.