DATALOAD - A USER-FRIENDLY PROGRAM TO PREPARE BINDING DATA FOR THE LIGAND SOFTWARE

This paper presents a program for the preparation of binding data to b e used with the LIGAND software. This program will analyze saturation and competition/displacement binding data, and prepare all the necessa ry files that provide the input values for the final processing by the LIGAND package. Features include choices of different units for speci fic activity of the labeled tracer, and screen editing of the data, an d results are provided as an average of replicates or as individual po ints. The program creates a graphic file to observe the raw data as a B/T vs T graph, prior to the analysis with the LIGAND program. The pro gram saves all the information in a session file. Calculation of the b ound/free values for the raw data is also provided.