WEGENER GRANULOMATOSIS WITH EXCLUSIVE REN AL INVOLVEMENT

Cases of Wegener's granulomatosis with exclusive renal involvement are very unusual. Here we report a patient who presented which acute rena l failure with massive extracapillary proliferation on renal biopsy, w ithout extrarenal manifestations. After 9 years on chronic hemodialysi s she developed several otorhinological abnormalities and finally pulm onary nodes. Lung biopsy showed a granulomatous vasculitis characteris tic of Wegener's granulomatosis. Wegener's disease can recur after pro longed asymptomatic periods. In those cases with exclusive renal invol vement, diagnosis can be delayed until the appearance of respiratory m anifestations.