EFFECT OF SUBINHIBITORY CONCENTRATIONS OF LOMEFLOXACIN ON BACTERIAL ADHERENCE

Authors
RAVIZZOLA G LONGO M POLLARA P DEFRANCESCO M PIZZI R
Citation
G. Ravizzola et al., EFFECT OF SUBINHIBITORY CONCENTRATIONS OF LOMEFLOXACIN ON BACTERIAL ADHERENCE, The New microbiologica, 17(3), 1994, pp. 211-216
Citations number
NO
Categorie Soggetti
Microbiology
Journal title
The New microbiologica
ISSN journal
11217138 → ACNP
Volume
17
Issue
3
Year of publication
1994
Pages
211 - 216
Database
ISI
SICI code
1121-7138(1994)17:3<211:EOSCOL>2.0.ZU;2-8
Abstract
We studied the effect of subinhibitory concentrations of lomefloxacin on bacterial adherence, assessing the presence of fimbriae in E. coli and the adherence to uroepithelial cells of Staphylococcus saprophytic us. The degree of inhibition of fimbriae in E. coli in the log-phase i s directly proportional to subminimal inhibiting concentrations (sub-M IC). On the contrary, there is no effect when the bacteria are in a st ationary phase. In the case of Staphylococcus saprophyticus the adhere nce to epithelial cells was observed at concentrations of 112 and 1/4 the MIC.