R. Nicosia et al., RATE OF OCCURRENCE OF HELICOBACTER-PYLORI IN PATIENTS WITH GASTRODUODENAL PATHOLOGY - PILOT RESEARCH, The New microbiologica, 17(3), 1994, pp. 217-223
In an attempt to establish the etiologic role of Helicobacter pylori (
H. pylori) in gastric and/or duodenal pathology, 169 patients were tes
ted and compared with a control group of 25 healthy subjects, for a to
tal of 194 subjects. Data on sex, age, familiarity, smoking, coffee an
d alcohol habits were collected and each patient underwent histologica
l, microbiological and immunological tests. 80 (41.2%) subjects were f
ound positive to H. pylori. This bacterium was detected in 53.3% of pa
tients with gastric ulcer while IgG were found in 86.7%; in 50% of pat
ients with chronic atrophic gastritis while IgG were detected in 80%;i
n 48.5% of patients with duodenal ulcer while IgG were found in 87.9%;
in 41.8% of patients with superficial chronic gastritis while IgG wer
e detected in 80.2%. In the control group of healthy patients H. pylor
i was found in 28% of patients while IgG were detected in 62.5%. The r
esults do not confirm a direct clear-cut correlation between this micr
organism and the pathologies studied.