SCALEUP OF PEROXIDASE PRODUCTION BY ARTHROMYCES-RAMOSUS BASED ON ANALYSIS OF FLUID VELOCITY DISTRIBUTION

Authors
TSUJIMURA H TAKAYA M KATANO K MATSUMOTO N PARK YS OKABE M
Citation
H. Tsujimura et al., SCALEUP OF PEROXIDASE PRODUCTION BY ARTHROMYCES-RAMOSUS BASED ON ANALYSIS OF FLUID VELOCITY DISTRIBUTION, Journal of fermentation and bioengineering, 77(6), 1994, pp. 650-654
Citations number
14
Categorie Soggetti
Food Science & Tenology","Biothechnology & Applied Migrobiology
Journal title
Journal of fermentation and bioengineering → ACNP
ISSN journal
0922338X
Volume
77
Issue
6
Year of publication
1994
Pages
650 - 654
Database
ISI
SICI code
0922-338X(1994)77:6<650:SOPPBA>2.0.ZU;2-N
Abstract
A fluid velocity distribution analysis was applied to a scaleup of per oxidase production by batch culture of Arthromyces ramosus. The scaleu ps from a 10 l jar-fermentor to 1 kl and 10 kl fermenters were carried out by minimizing deviation in the velocity distribution from that of a 10 1 jar-fermenter. By this method, agitation rates in 1 kl and 10 kl fermenters were determined as 190 and 90 rpm, respectively. The per oxidase activity obtained in both 1 kl and 10 kl fermenters was 40 U/m l after a 90 h culture, which is consistent with that obtained in 10 l jar-fermenter.