The high resolution CT (HRCT) findings in an adult with disseminated t
racheobronchial papillomatosis are discussed. In addition to polypoid
masses within the trachea and main bronchi, diffuse ill-defined parenc
hymal centrilobular opacities were present; these reflect lesions with
in the small airways. Some of the nodules showed central cavitation. I
n a patient with centrilobular opacities, some of which cavitate, on H
RCT and concomitant endobronchial or endotracheal abnormality, dissemi
nated papillomatosis should be considered in the differential diagnosi
s, particularly if there is a history of hoarseness or laryngeal disea
se.