P. Kleinebudde et al., THE POWER-CONSUMPTION-CONTROLLED EXTRUDER - A TOOL FOR PELLET PRODUCTION, Journal of Pharmacy and Pharmacology, 46(7), 1994, pp. 542-546
Based on the assumption that there is a link between power consumption
of an extruder and pellet properties, a control circuit for power con
sumption was developed. Powder and granulation liquid are feeded separ
ately into a twin-screw extruder. The power consumption is controlled
by varying the pump rate at a given powder-feed rate; consequently eac
h level of power consumption results in a specific water content of th
e extrudate for a particular formulation. The shape of pellets depends
almost entirely on the level of power consumption irrespective of for
mulation. The size of dry pellets is additionally affected by a shrink
ing factor which depends on the water content. The power-consumption-c
ontrolled extruder is an appropriate tool for the production of pellet
s. The system is able to adapt the water content for a formulation aut
omatically.