N. Muller et al., TOURETTES-SYNDROME ASSOCIATED WITH RESTLESS LEGS SYNDROME AND AKATHISIA IN A FAMILY, Acta neurologica Scandinavica, 89(6), 1994, pp. 429-432
A family with coincidence of a restless leg syndrome (RLS) in the moth
er and a Gilles de la Tourette syndrome (GTS) in the son who also show
s increased vulnerability to neuroleptic induced akathisia (NIA) is pr
esented. Since these diseases show parallels from a genetic, pathogene
tic and clinical point of view, the familiar coincidence is discussed
under these aspects with respect to suggested disturbances of the dopa
mine and the opiate systems in RLS, GTS, and NIA.